Smart Health Alliance
Smart Health Alliance enables Life Sciences sponsors to activate multicountry, longitudinal real-world evidence programmes while helping healthcare organisations participate in high-value research through a governed, privacy-preserving model.
SHA centres have completed a technical and scientific certification process, ensuring data quality, governance, and operational readiness for sponsored research.
Powered by Savana’s infrastructure, Smart Health Alliance connects Life Sciences sponsors with fit-for-purpose clinical data while enabling healthcare organisations to participate in high-value research without transferring raw data or building research infrastructure from scratch.
SHA centres have completed a scientific certification process. Data is pre-verified as recoverable, structurable, and ready for regulatory-grade analysis. Sponsors commit knowing the data is fit for purpose – not as a promise, but as a pre-verified characteristic of each centre.
Move faster from protocol to first data
Savana already knows each SHA centre’s IT environment, integration constraints, and regulatory processes. No discovery phase, no de-identification deployment to negotiate, no committees to map from scratch. That eliminates weeks of start-up and makes timelines predictable.
Expand cohorts, variables, and geographies without rebuilding
The infrastructure stays once it is live. Sponsors can add new variables, new therapeutic areas, new cohorts, or new sites – fit for purpose to each programme’s needs – without building relationships from scratch. The marginal cost of each new study is materially lower than the first.
Compounding scientific value
Each Living Evidence Hub contributes to a growing ecosystem of validated variables, reusable cohorts, disease expertise and operational experience. Sponsors benefit from an infrastructure that becomes more capable over time rather than starting from scratch with every study.
One network for prelaunch, launch, and post-launch RWE needs
The infrastructure you won’t have to build
Without SHA, sponsors fund technical discovery, de-identification deployment, and regulatory navigation at each centre independently. That replication cost – in time, budget, and planning risk – is substantial. It is also the real switching cost of not working with Savana.
SHA is designed to incorporate new sites fit for purpose to each sponsor’s programme – specific patient profiles, geographies, or specialities not yet covered can be activated without rebuilding the governance or technical framework. This is what makes SHA structurally different from fixed-catalogue models.
Evidence that supports regulatory strategies
Regulatory-grade real-world evidence designed to support critical decisions across the product lifecycle, from early asset strategy and evidence planning through regulatory interactions with agencies such as the FDA and EMA, market access, medical affairs, launch readiness and commercial operations.
Peer-reviewed scientific output
Publications in leading journals validate both the methodological rigour and the real-world applicability of the approach across disease areas.
Validated in real clinical environments
Demonstrated across live hospital settings, supporting accuracy, scalability, and integration into clinical and research workflows at scale.
Trusted by global Life Sciences organisations
The ten largest pharmaceutical companies globally work with Savana – evidence that the infrastructure delivers at the level regulatory and medical affairs teams require.
Your Challenge
Expand research capacity and institutional visibility while protecting resources, budgets, and day-to-day operational priorities.
What SHA offers you
Participate in a permanent international research infrastructure, increase scientific visibility, access future multicentre collaborations and generate value from clinical data without transferring raw data or building research infrastructure from scratch.
Your Challenge
Support research collaboration without increasing integration complexity, infrastructure burden, or cybersecurity exposure.
What SHA offers you
A federated model where raw data stays within your institution at all times. Collaboration happens through structured, locally processed outputs – no centralisation, no data transfer, minimal technical disruption.
Your Challenge
Improve care pathways and clinical decision-making while ensuring research initiatives stay grounded in real-world practice.
What SHA offers you
Access structured longitudinal evidence derived from routine clinical care, supporting pathway understanding, clinical insight generation, and participation in research programmes that feed back into practice.
Your Challenge
Launch multicentre studies faster, access broader and more representative cohorts, and reduce the operational burden of building research infrastructure from scratch.
What SHA offers you
Reusable governance and technical frameworks, multicountry collaboration, and pre-certified clinical data assets that accelerate study setup and support scalable, longitudinal evidence generation.
Your Challenge
Enable research collaboration while maintaining data sovereignty, privacy safeguards, and compliance with local and European regulatory requirements.
What SHA offers you
A privacy-preserving federated model built on the principle that raw data never leaves the institution. Designed for GDPR compliance and aligned with evolving EHDS requirements, with local governance maintained at every stage.
Savana assesses your institution's technical readiness and certifies data recoverability, structurability, and fit for regulatory-grade use – the Site Assessment.
Sign the GDPR-compliant SHA agreement and activate the governance framework that lets you start collaborating securely with sponsored research programmes.
Your dataset catalogue is published in Savana Data Space, making it discoverable to authorised research sponsors and opening the door to new evidence generation projects.
* Already a Savana client? Institutions that deploy Savana technology or have participated in a sponsored evidence programme may qualify for direct membership. Speak to your account team.
Talk to us about designing a multicentre, longitudinal RWE programme on top of the SHA network.
Participate in sponsored research, generate scientific value, and maintain full control of your data.
Stay ahead of how real-world data is reshaping clinical practice, drug development, and healthcare policy.
